CARES Video Script [Introduction to Study] Meet Lisa. She is going to have surgery soon. She wants to get better after surgery with as little pain as possible. But she worries that her pain medicine may have side effects. Fortunately, doctors know of two very helpful ways to treat pain after surgery. But doctors do not know which way works the best or has the fewest side effects. Enter CARES, a study that compares two effective and commonly used ways to treat pain after surgery. CARES will help people like Lisa, her family, and doctors know which way treats pain the best. [What is participation in the study like?] If you join CARES, you will receive one of two types of pain medication for home after surgery. One group will get prescriptions for the pain relievers acetaminophen plus NSAIDs. The other group will get prescriptions for acetaminophen, plus a small amount of an opioid. We will ask you to complete surveys on a smartphone. Surveys take place the week before surgery, after surgery every day for one week, Then at 1 month, 3 months, and 6 months. A survey may take less than a minute or over 10 minutes. We will also gather necessary information from your medical records. [Closing/Potential risks] In CARES, it is very important to us that your pain is well controlled. The main risk of the study is the need to ask for another prescription for pain medicine. You can get more pain medicine even if you join the study. But needing extra is unlikely. We have steps in place to help you manage pain. First, we already know both ways work well to manage pain. Doctors use both ways for patients not in this study. Second, both ways include acetaminophen at stronger, prescription-strength doses. Back to Lisa. By joining CARES, she helped her family, doctors, and other patients know which way treats pain the best after surgery.